isoThiocyanates. XXVI. Straight-Chain omega-Methylthioalkyl isoThiocyanates and some Derivatives.
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چکیده
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Hydroxy Isothiocyanates
antifungal and antibacterial activities at concentrations of 7.8 to 15,6uglml, respectively, and that a possible target of the ITC compounds might be the cellular sulfhydryl group, In recent years, a number of multidrug transporters have been found in various organisms including bacteria and human cells.3) A promising way to conquer such multidrug resistance is to inactivate the eMux protein in...
متن کاملIsothiocyanates: a review
Isothiocyanates (ITCs) are naturally occurring molecules belonging to highly reactive organosulphur synthons, with the general structure R–N=C=S. The precursor molecule glucosinolate anions are hydrolyzed enzymatically (under the effect of myrosinase enzymes) or unenzymatically to produce nitriles or isothiocyanates depending upon conditions such as pH and temperature. Brassicaceae Family is k...
متن کاملGlucosinolates, isothiocyanates and indoles
Although isothiocyanate and indole compounds derived from cruciferous vegetables appear to be structurally unrelated, they are both derived from glucosinolates. These sulfur-containing glycosides are found in the order Capparales, which includes the large family Brassicaceae. The glucosinolate molecule comprises a common glucone moiety and a variable aglucone side-chain, derived from one of sev...
متن کاملChemoprevention by isothiocyanates.
Naturally occurring and synthetic isothiocyanates are among the most effective chemopreventive agents known. A wide variety of isothiocyanates prevents cancer in the rat lung, mammary gland, esophagus, liver, small intestine, colon, and bladder. Mechanistic studies have shown that this chemopreventive activity is due to favorable modification of phase I and phase II carcinogen metabolism, resul...
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This paper deals with the synthesis of three up to date not described 4-(£>-terphenylyl)isothiocyanates and their six intermediates, two of which having not been described, too. A procedure was developed to identify £>-terphenyl derivatives by means of thin layer chromatography on alumina, as well as by gas chromatography. Infra-red and ultra-violet spectra were taken of the synthetized 4-(30-t...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1957
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.11-1298